For node.js applications, you can enable SSL on the application side or using Nginx or Apache running as a reverse proxy. To enable SSL for a node.js express application, use the following code.
const fs = require('fs')
const https = require('https')
const express = require('express')
var port = 3000;
var options = {
key: fs.readFileSync('./ssl/ssl.key'),
cert: fs.readFileSync('./ssl/ssl.crt'),
};
var app = express();
var server = https.createServer(options, app).listen(port, function(){
console.log("Express server listening on port " + port);
});
app.get('/', function (req, res) {
res.writeHead(200);
res.end("hello world\n");
});
See node.js